AiRMOUR focuses on research and validating novel concepts and solutions to make urban air mobility safe, secure, quiet and green but also more accessible, faster, affordable and publicly accepted. In response to the call, AiRMOUR presents an approach that takes on one of the most critical and challenging early real life applications of UAM in Emergency Medical Services (EMS). EMS provides a versatile scenario pool that facilitates thoroughly investigating the urgent challenges at hand applying a result driven quadruple helix approach. AiRMOUR fills in the excellence gaps and drastically advances the understanding of needed near-future actions by urban communities, operators, regulators, academia and businesses. The approach and the outcomes will massively benefit the entire UAM development in EMS, but also widely within e.g. the vision of true airborne mobility genuinely supplementing traditional transport modes. AiRMOUR concept centers on thorough research of safety, regulation, user acceptance, sustainability; leveraging them into practical and real-life tangible UAM tools after TRL6 live validations. A strong consortium of research, national aviation, regional and local urban authorities, UAM operators and EMS can guide cities making sure that the impacts are replicated widely. Main outputs are UAM toolbox with a UAM GIS tool for authorities, a UAM guidebook (for cities, operators and other stakeholders) and a UAM training programme together with Eurocontrol, all tested by cities and replicators. The crucial impact of AiRMOUR will be increased UAM competence of city and regional staff and their partners in public transport, energy, innovation and funding. Participation in AiRMOUR allows hands-on testing of the UAM toolbox as well as take-up of future UAM scenarios. Each European local cluster of aviation and urban actors will be able to set-up their own UAM realisation. European policy making and investments will be reinforced with AiRMOUR findings and knowledge.